منابع مشابه
Structure of cone photoreceptors.
Although outnumbered more than 20:1 by rod photoreceptors, cone cells in the human retina mediate daylight vision and are critical for visual acuity and color discrimination. A variety of human diseases are characterized by a progressive loss of cone photoreceptors but the low abundance of cones and the absence of a macula in non-primate mammalian retinas have made it difficult to investigate c...
متن کاملA cone theoretic Krein-Milman theorem in semitopological cones
In this paper, a Krein-Milman type theorem in $T_0$ semitopological cone is proved, in general. In fact, it is shown that in any locally convex $T_0$ semitopological cone, every convex compact saturated subset is the compact saturated convex hull of its extreme points, which improves the results of Larrecq.
متن کاملLoss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival.
Cones are the primary photoreceptor (PR) cells responsible for vision in humans. They are metabolically highly active requiring phosphoinositide 3-kinase (PI3K) activity for long-term survival. One of the downstream targets of PI3K is the kinase mammalian target of rapamycin (mTOR), which is a key regulator of cell metabolism and growth, integrating nutrient availability and growth factor signa...
متن کاملCone and rod function in cone degenerations
Progressive cone dystrophy (CD) is usually marked in the initial stages by reduced visual acuity, color vision deficiency and alterations in the photopic electroretinogram, while morphological alterations can be very mild; in some forms rods are affected in a later stage as well. We examined 40 patients with progressive cone dystrophy to determine the extent of functional losses in the cone sys...
متن کاملGenotype-dependent variability in residual cone structure in achromatopsia: toward developing metrics for assessing cone health.
PURPOSE Gene therapy trials for inherited photoreceptor disorders are planned. Anatomical metrics to select the best candidates and outcomes are needed. Adaptive optics (AO) imaging enables visualization of photoreceptor structure, although analytical tools are lacking. Here we present criteria to assess residual photoreceptor integrity in achromatopsia (ACHM). METHODS Two AOSLOs, at the Medi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Geological Magazine
سال: 1888
ISSN: 0016-7568,1469-5081
DOI: 10.1017/s0016756800183037